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Genetic polymorphisms in the cyclooxygenase-1 and cyclooxygenase-2 genes and risk of colorectal adenoma

PURPOSE: Cyclooxygenase (COX) enzymes, COX1 and COX2, are key in converting arachidonic acid (AA) into prostaglandins that have been associated with colorectal carcinogenesis. The aim of our study was to investigate associations of polymorphisms in COX genes, alone and in interaction with exposures...

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Detalhes bibliográficos
Main Authors: Gong, Zhihong, Bostick, Roberd M., Xie, Dawen, Hurley, Thomas G., Deng, Zonglin, Dixon, Dan A., Zhang, Jinhui, Hebert, James R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461962/
https://ncbi.nlm.nih.gov/pubmed/19205707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00384-009-0656-8
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