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Thermodynamic Analysis of Protegrin-1 Insertion and Permeation through a Lipid Bilayer
Molecular dynamics (MD) simulations are used to study the pathway for the insertion of the cationic antimicrobial peptide protegrin-1 (PG1) into mixed anionic lipid bilayers composed of palmitoyl-oleoyl-phosphatidylglycerol (POPG) and palmitoyl-oleoyl-phosphatidylethanolamine (POPE) in a 1:3 ratio (...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3461958/ https://ncbi.nlm.nih.gov/pubmed/22044268 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp205153y |
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