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Functional genetic variation in the Rev-Erbα pathway and lithium response in the treatment of bipolar disorder

Bipolar disorder (BD) is characterized by disruptions in circadian rhythms such as sleep and daily activity that often normalize after lithium treatment in responsive patients. Since lithium is known to interact with the circadian clock, we hypothesized that variation in circadian “clock genes” woul...

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Autori principali: McCarthy, Michael J., Nievergelt, Caroline M., Shekhtman, Tatyana, Kripke, Daniel F., Welsh, David K., Kelsoe, John R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461952/
https://ncbi.nlm.nih.gov/pubmed/21781277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1601-183X.2011.00725.x
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