SLC26A9-mediated chloride secretion prevents mucus obstruction in airway inflammation

Asthma is a chronic condition with unknown pathogenesis, and recent evidence suggests that enhanced airway epithelial chloride (Cl(–)) secretion plays a role in the disease. However, the molecular mechanism underlying Cl(–) secretion and its relevance in asthma pathophysiology remain unknown. To det...

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Библиографические подробности
Главные авторы: Anagnostopoulou, Pinelopi, Riederer, Brigitte, Duerr, Julia, Michel, Sven, Binia, Aristea, Agrawal, Raman, Liu, Xuemei, Kalitzki, Katrin, Xiao, Fang, Chen, Mingmin, Schatterny, Jolanthe, Hartmann, Dorothee, Thum, Thomas, Kabesch, Michael, Soleimani, Manoocher, Seidler, Ursula, Mall, Marcus A.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2012
Предметы:
Brief Report
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461899/
https://ncbi.nlm.nih.gov/pubmed/22945630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI60429
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