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Inheritance of DNA methylation in microinjected eggs of Xenopus laevis.

Plasmid DNA methylated at Hpa II sites was injected into eggs of Xenopus laevis. The methylated DNA replicates extrachromosomally, and the methylated state of the H pa II sites is inherited through replication. Unmethylated sites remain unmethylated in progeny molecules. To test whether replication...

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Bibliographic Details
Main Author: Harland, R M
Format: Artigo
Language:Inglês
Published: 1982
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC346185/
https://ncbi.nlm.nih.gov/pubmed/6285378
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