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Paradoxical effects of glucocorticoids on regulation of plasminogen activator activity of rat hepatoma cells.

Incubation of rat hepatoma cells with cAMP derivatives stimulates cell-associated plasminogen activator activity 8- to 22-fold and extracellular plasminogen activator activity 30- to 1300-fold. This time- and concentration-dependent increase is enhanced by phosphodiesterase inhibitors. Dexamethasone...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Barouski-Miller, P A, Gelehrter, T D
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1982
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346184/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6179095/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.7.2319
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