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Tug of war in the haematopoietic stem cell niche: do myeloma plasma cells compete for the HSC niche?

In the adult mammal, normal haematopoiesis occurs predominantly in the bone marrow, where primitive haematopoietic stem cells (HSC) and their progeny reside in specialised microenvironments. The bone marrow microenvironment contains specific anatomical areas (termed niches) that are highly specialis...

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Detalhes bibliográficos
Main Authors: Noll, J E, Williams, S A, Purton, L E, Zannettino, A C W
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461708/
https://ncbi.nlm.nih.gov/pubmed/22983434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bcj.2012.38
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