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Use of monoclonal antibodies to subunits of human chorionic gonadotropin to examine the orientation of the hormone in its complex with receptor.

Monoclonal antibodies were prepared against the alpha and beta subunits of human chorionic gonadotropin (hCG). Although all were selected on the basis of their ability to bind the intact hormone, each also bound one of the two subunits but not both. Using a solid phase double antibody system to meas...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Moyle, W R, Ehrlich, P H, Canfield, R E
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1982
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346168/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6285376/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.7.2245
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