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Mutant lambda phage repressor with a specific defect in its positive control function.

The lambda phage repressor is both a positive and a negative regulator of gene transcription. We describe a mutant lambda phage repressor that has specifically lost its activator function. The mutant binds to the lambda phage operator sites and represses the lambda phage promoters PR and PL. However...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Guarente, L, Nye, J S, Hochschild, A, Ptashne, M
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1982
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346166/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6212933/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.7.2236
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