Physiological Modeling of Responses to Upper Versus Lower Lobe Lung Volume Reduction in Homogeneous Emphysema

Rationale: In clinical trials, homogeneous emphysema patients have responded well to upper lobe volume reduction but not lower lobe volume reduction. Materials/Methods: To understand the physiological basis for this observation, a computer model was developed to simulate the effects of upper and low...

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Bibliographic Details
Main Authors: Valipour, Arschang, Kramer, Mordechai R., Stanzel, Franz, Kempa, Axel, Asadi, Sherwin, Fruchter, Oren, Eberhardt, Ralf, Herth, Felix J., Ingenito, Edward P.
Format: Artigo
Language:Inglês
Published: Frontiers Research Foundation 2012
Subjects:
Physiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461642/
https://ncbi.nlm.nih.gov/pubmed/23060811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2012.00387
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