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DNA precursor pool: a significant target for N-methyl-N-nitrosourea in C3H/10T1/2 clone 8 cells.

Synchronized C3H/10T1/2 clone 8 cells were treated in vitro with a nontoxic dose of N-methyl-N-nitrosourea during their S phase. Chromatographic isolation of the deoxyribonucleotide DNA precursor pool and measurement of the precursor content per cell showed that a nucleic acid residue in the precurs...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Topal, M D, Baker, M S
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1982
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346161/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6954535/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.7.2211
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