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Bone Marrow and Peripheral Blood AML Cells Are Highly Sensitive to CNDAC, the Active Form of Sapacitabine

Achieving improvements in survival and reducing relapse remains a challenge in acute myelogenous leukemia (AML) patients. This study evaluated the in vitro efficacy of the active form of novel agent sapacitabine, CNDAC, compared to current chemotherapeutic drugs Ara-C and mitoxantrone using two AML...

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Autors principals: Jagan, Sucheta, Paganessi, Laura A., Frank, Robin R., Venugopal, Parameswaran, Larson, Melissa, Christopherson, Kent W.
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461608/
https://ncbi.nlm.nih.gov/pubmed/23049558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/727683
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