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Importance of Stress Receptor-Mediated Mechanisms in the Amygdala on Visceral Pain Perception in an Intrinsically Anxious Rat

BACKGROUND: Stress worsens abdominal pain experienced by patients with irritable bowel syndrome (IBS), a chronic disorder of unknown origin with comorbid anxiety. We have previously demonstrated colonic hypersensitivity in Wistar-Kyoto rats (WKYs), a high-anxiety strain, that models abdominal pain i...

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Detalhes bibliográficos
Main Authors: Johnson, Anthony C., Tran, Lee, Schulkin, Jay, Greenwood-Van Meerveld, Beverley
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461498/
https://ncbi.nlm.nih.gov/pubmed/22364507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2982.2012.01899.x
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