Curcumin–cyclodextrin complexes potentiate gemcitabine effects in an orthotopic mouse model of lung cancer

BACKGROUND: Overall clinical outcome for advanced lung cancer remains very disappointing despite recent advances in treatment. Curcumin has been reported as potentially active against cancer. METHODS: Owing to poor curcumin solubility, we have used cyclodextrins (CD) as an excipient allowing a consi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Rocks, N, Bekaert, S, Coia, I, Paulissen, G, Gueders, M, Evrard, B, Van Heugen, J-C, Chiap, P, Foidart, J-M, Noel, A, Cataldo, D
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2012
Schlagworte:
Translational Therapeutics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461170/
https://ncbi.nlm.nih.gov/pubmed/22929882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.379
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