Epigenetic remodelling of gene expression profiles of neoplastic and normal tissues: immunotherapeutic implications

BACKGROUND: Epigenetic remodelling of cancer cells is an attractive therapeutic strategy and distinct DNA hypomethylating agents (DHA) are being actively evaluated in patients with hemopoietic or solid tumours. However, no studies have investigated the modulation of gene expression profiles (GEP) in...

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Detalhes bibliográficos
Main Authors: Coral, S, Covre, A, JMG Nicolay, H, Parisi, G, Rizzo, A, Colizzi, F, Dalla Santa, S, Fonsatti, E, Fratta, E, Sigalotti, L, Maio, M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Translational Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461156/
https://ncbi.nlm.nih.gov/pubmed/22910318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.361
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