Polymorphisms in the myeloperoxidase gene locus are associated with acute kidney injury-related outcomes

Myeloperoxidase (MPO) is a lysosomal enzyme that may be involved in oxidative stress-mediated kidney injury. Using a 2-step approach, we measured the association of 4 polymorphisms across the length of the MPO gene with systemic markers of oxidative stress; plasma MPO and urinary 15-F(2t)-isoprostan...

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Hauptverfasser: Perianayagam, Mary C., Tighiouart, Hocine, Liangos, Orfeas, Kouznetsov, Diana, Wald, Ron, Rao, Fangwen, O’Connor, Daniel T., Jaber, Bertrand L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461107/
https://ncbi.nlm.nih.gov/pubmed/22739978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2012.235
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