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Implication of DNA Demethylation and Bivalent Histone Modification for Selective Gene Regulation in Mouse Primordial Germ Cells

Primordial germ cells (PGCs) sequentially induce specific genes required for their development. We focused on epigenetic changes that regulate PGC-specific gene expression. mil-1, Blimp1, and Stella are preferentially expressed in PGCs, and their expression is upregulated during PGC differentiation....

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Detalhes bibliográficos
Main Authors: Mochizuki, Kentaro, Tachibana, Makoto, Saitou, Mitinori, Tokitake, Yuko, Matsui, Yasuhisa
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461056/
https://ncbi.nlm.nih.gov/pubmed/23029374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046036
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