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Implication of DNA Demethylation and Bivalent Histone Modification for Selective Gene Regulation in Mouse Primordial Germ Cells

Primordial germ cells (PGCs) sequentially induce specific genes required for their development. We focused on epigenetic changes that regulate PGC-specific gene expression. mil-1, Blimp1, and Stella are preferentially expressed in PGCs, and their expression is upregulated during PGC differentiation....

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Bibliografiske detaljer
Main Authors: Mochizuki, Kentaro, Tachibana, Makoto, Saitou, Mitinori, Tokitake, Yuko, Matsui, Yasuhisa
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461056/
https://ncbi.nlm.nih.gov/pubmed/23029374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046036
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