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Analyzing Gene Expression from Whole Tissue vs. Different Cell Types Reveals the Central Role of Neurons in Predicting Severity of Alzheimer’s Disease

Alterations in gene expression resulting from Alzheimer’s disease have received considerable attention in recent years. Although expression has been investigated separately in whole brain tissue, in astrocytes and in neurons, a rigorous comparative study quantifying the relative utility of these sou...

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Detalhes bibliográficos
Main Authors: Stempler, Shiri, Ruppin, Eytan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461041/
https://ncbi.nlm.nih.gov/pubmed/23029292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045879
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