Potential Role of M. tuberculosis Specific IFN-γ and IL-2 ELISPOT Assays in Discriminating Children with Active or Latent Tuberculosis

BACKGROUND: Although currently available IGRA have been reported to be promising markers for TB infection, they cannot distinguish active tuberculosis (TB) from latent infection (LTBI). OBJECTIVE: Children with LTBI, active TB disease or uninfected were prospectively evaluated by an in-house ELISPOT...

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Main Authors: Chiappini, Elena, Della Bella, Chiara, Bonsignori, Francesca, Sollai, Sara, Amedei, Amedeo, Galli, Luisa, Niccolai, Elena, Del Prete, Gianfranco, Singh, Mahavir, D'Elios, Mario M., de Martino, Maurizio
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461005/
https://ncbi.nlm.nih.gov/pubmed/23029377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046041
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