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An adaptive weighted ensemble procedure for efficient computation of free energies and first passage rates

We introduce an adaptive weighted-ensemble procedure (aWEP) for efficient and accurate evaluation of first-passage rates between states for two-state systems. The basic idea that distinguishes aWEP from conventional weighted-ensemble (WE) methodology is the division of the configuration space into s...

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Detalhes bibliográficos
Main Authors: Bhatt, Divesh, Bahar, Ivet
Formato: Artigo
Idioma:Inglês
Publicado em: American Institute of Physics 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460967/
https://ncbi.nlm.nih.gov/pubmed/22979844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.4748278
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