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The Polyoma Virus Large T Binding Protein p150 Is a Transcriptional Repressor of c-MYC
p150, product of the SALL2 gene, is a binding partner of the polyoma virus large T antigen and a putative tumor suppressor. p150 binds to the nuclease hypersensitive element of the c-MYC promoter and represses c-MYC transcription. Overexpression of p150 in human ovarian surface epithelial cells lead...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3460914/ https://ncbi.nlm.nih.gov/pubmed/23029531 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046486 |
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