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Subdominant Antigens in Bacterial Vaccines: AM779 Is Subdominant in the Anaplasma marginale Outer Membrane Vaccine but Does Not Associate with Protective Immunity

Identification of specific antigens responsible for the ability of complex immunogens to induce protection is a major goal in development of bacterial vaccines. Much of the investigation has focused on highly abundant and highly immunodominant outer membrane proteins. Recently however, genomic and p...

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Autors principals: Albarrak, Saleh M., Brown, Wendy C., Noh, Susan M., Reif, Kathryn E., Scoles, Glen A., Turse, Joshua E., Norimine, Junzo, Ueti, Massaro W., Palmer, Guy H.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460813/
https://ncbi.nlm.nih.gov/pubmed/23029498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046372
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