Cellular location affects protein stability in Escherichia coli.
We study the biosynthesis of preproinsulin and proinsulin in Escherichia coli by pulse-chase experiments. When E. coli is transformed with plasmids bearing a gene consisting of a fusion of preproinsulin DNA to part or to all of the DNA encoding a bacterial signal sequence, a variety of hybrid prepro...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1982
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346074/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7043465/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.6.1830 |
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