Gene expression signatures modulated by epidermal growth factor receptor activation and their relationship to cetuximab resistance in head and neck squamous cell carcinoma

BACKGROUND: Aberrant activation of signaling pathways downstream of epidermal growth factor receptor (EGFR) has been hypothesized to be one of the mechanisms of cetuximab (a monoclonal antibody against EGFR) resistance in head and neck squamous cell carcinoma (HNSCC). To infer relevant and specific...

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Main Authors: Fertig, Elana J, Ren, Qing, Cheng, Haixia, Hatakeyama, Hiromitsu, Dicker, Adam P, Rodeck, Ulrich, Considine, Michael, Ochs, Michael F, Chung, Christine H
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460736/
https://ncbi.nlm.nih.gov/pubmed/22549044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-160
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