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Origins of Stereoselectivities of Dihydroxylations of cis-Bicyclo[3.3.0]octenes

Stereoselectivities of the dihydroxylations of cis-bicyclo[3.3.0]octene intermediates for a projected total synthesis of chromodorolide A have been explored experimentally. The reaction occurs unexpectedly on the apparently more hindered (concave) face; this result has been explained through computa...

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Detalhes bibliográficos
Main Authors: Wang, Hao, Kohler, Philipp, Overman, Larry E., Houk, K. N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460691/
https://ncbi.nlm.nih.gov/pubmed/22954350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja3075538
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