Efficient generation, purification, and expansion of CD34(+) hematopoietic progenitor cells from nonhuman primate–induced pluripotent stem cells

Induced pluripotent stem cell (iPSC) therapeutics are a promising treatment for genetic and infectious diseases. To assess engraftment, risk of neoplastic formation, and therapeutic benefit in an autologous setting, testing iPSC therapeutics in an appropriate model, such as the pigtail macaque (Maca...

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Hlavní autoři: Gori, Jennifer L., Chandrasekaran, Devikha, Kowalski, John P., Adair, Jennifer E., Beard, Brian C., D'Souza, Sunita L., Kiem, Hans-Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2012
Témata:
Hematopoiesis and Stem Cells
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460690/
https://ncbi.nlm.nih.gov/pubmed/22898598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-05-433797
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