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Application of MassSQUIRM for Quantitative Measurements of Lysine Demethylase Activity

Recently, epigenetic regulators have been discovered as key players in many different diseases (1-3). As a result, these enzymes are prime targets for small molecule studies and drug development( 4). Many epigenetic regulators have only recently been discovered and are still in the process of being...

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Hlavní autoři: Blair, Lauren P., Avaritt, Nathan L., Tackett, Alan J.
Médium: Artigo
Jazyk:Inglês
Vydáno: MyJove Corporation 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460583/
https://ncbi.nlm.nih.gov/pubmed/22433969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/3604
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