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Transcriptional regulation of BRCA1 expression by a metabolic switch
Though the linkages between germline mutations of BRCA1 and hereditary breast cancer are well known, recent evidence suggests that altered BRCA1 transcription may also contribute to sporadic forms of breast cancer. Here we show that BRCA1 expression is controlled by a dynamic equilibrium between tra...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3460552/ https://ncbi.nlm.nih.gov/pubmed/21102443 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1941 |
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