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Reciprocal modulation of agonist and antagonist binding to muscarinic cholinergic receptor by guanine nucleotide.

The ability of guanine nucleotide to decrease the binding affinity of agonists but not antagonists has been documented in a number of hormone and neurotransmitter receptor systems. By contrast, recent reports indicate that both agonist and antagonist binding to the muscarinic cholinergic receptors a...

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Autores principales: Burgisser, E, De Lean, A, Lefkowitz, R J
Formato: Artigo
Lenguaje:Inglês
Publicado: 1982
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC346054/
https://ncbi.nlm.nih.gov/pubmed/6979043
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