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Synergistic Effects of Interleukin-7 and Pre-T Cell Receptor Signaling in Human T Cell Development
The role of IL-7 in pre-T cell receptor (TCR) signaling during human T cell development is poorly understood. To study this, we engineered Molt3, a T cell progenitor T-acute lymphoblastic leukemia cell line, using lentiviral IL-7 receptor α (IL-7Rα) to serve as a model system. IL-7 promoted pre-TCR...
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| Asıl Yazarlar: | , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Biochemistry and Molecular Biology
2012
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3460477/ https://ncbi.nlm.nih.gov/pubmed/22859301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.380113 |
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