Multiplexed Activity-based Protein Profiling of the Human Pathogen Aspergillus fumigatus Reveals Large Functional Changes upon Exposure to Human Serum

Environmental adaptability is critical for survival of the fungal human pathogen Aspergillus fumigatus in the immunocompromised host lung. We hypothesized that exposure of the fungal pathogen to human serum would lead to significant alterations to the organism's physiology, including metabolic...

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Autores principales: Wiedner, Susan D., Burnum, Kristin E., Pederson, LeeAnna M., Anderson, Lindsey N., Fortuin, Suereta, Chauvigné-Hines, Lacie M., Shukla, Anil K., Ansong, Charles, Panisko, Ellen A., Smith, Richard D., Wright, Aaron T.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Genomics and Proteomics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460446/
https://ncbi.nlm.nih.gov/pubmed/22865858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.394106
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