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Raf-1 Kinase Inhibitory Protein (RKIP) Mediates Ethanol-induced Sensitization of Secretagogue Signaling in Pancreatic Acinar Cells

Excessive alcohol consumption is associated with most cases of chronic pancreatitis, a progressive necrotizing inflammatory disease that can result in pancreatic insufficiency due to acinar atrophy and fibrosis and an increased risk of pancreatic cancer. At a cellular level acute alcohol exposure ca...

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Main Authors: Kim, Sung Ok, Ives, Kirk L., Wang, Xiaofu, Davey, Robert A., Chao, Celia, Hellmich, Mark R.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460440/
https://ncbi.nlm.nih.gov/pubmed/22859298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.367656
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