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Identification of Conserved Amino Acids in the Herpes Simplex Virus Type 1 UL8 Protein Required for DNA Synthesis and UL52 Primase Interaction in the Virus Replisome

We have used oriS-dependent transient replication assays to search for species-specific interactions within the herpes simplex virus replisome. Hybrid replisomes derived from herpes simplex virus type 1 (HSV-1) and equine herpesvirus type 1 (EHV-1) failed to support DNA replication in cells. Moreove...

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Hlavní autoři: Muylaert, Isabella, Zhao, Zhiyuan, Andersson, Torbjörn, Elias, Per
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460421/
https://ncbi.nlm.nih.gov/pubmed/22851167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.356782
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