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Novel insight into mechanisms of cholestatic liver injury

Cholestasis results in a buildup of bile acids in serum and in hepatocytes. Early studies into the mechanisms of cholestatic liver injury strongly implicated bile acid-induced apoptosis as the major cause of hepatocellular injury. Recent work has focused both on the role of bile acids in cell signal...

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Detalhes bibliográficos
Main Authors: Woolbright, Benjamin L, Jaeschke, Hartmut
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Co., Limited 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460324/
https://ncbi.nlm.nih.gov/pubmed/23049206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v18.i36.4985
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