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Matrix-independent Survival of Human Keratinocytes through an EGF Receptor/MAPK-Kinase-dependent Pathway

Normal epithelial cells undergo apoptosis when they are denied contact with the extracellular matrix, in a process termed “anoikis.” Conversely, malignant epithelial cells typically acquire anchorage independence, i.e., the capacity to survive and grow in the absence of matrix interaction. Here we a...

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Autores principales: Jost, Monika, Huggett, Teresa M., Kari, Csaba, Rodeck, Ulrich
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Cell Biology 2001
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC34602/
https://ncbi.nlm.nih.gov/pubmed/11359940
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