Loss of ARID1A expression is an early molecular event in tumor progression from ovarian endometriotic cyst to clear cell and endometrioid carcinoma

OBJECTIVES: ARID1A is a recently identified tumor suppressor participating in chromatin remodeling. Somatic inactivating mutations of ARID1A and loss of its expression occur most frequently in ovarian clear cell and endometrioid carcinomas and uterine endometrioid carcinomas. Since endometriosis is...

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Bibliographische Detailangaben
Hauptverfasser: Ayhan, Ayse, Mao, Tsui-Lien, Seckin, Tamer, Wu, Chen-Hsuan, Guan, Bin, Ogawa, Hiroshi, Futagami, Masayuki, Mizukami, Hiroki, Yokoyama, Yoshihito, Kurman, Robert J., Shih, Ie-Ming
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460070/
https://ncbi.nlm.nih.gov/pubmed/22976498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/IGC.0b013e31826b5dcc
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