Multiple quantitative trait loci for cortical and trabecular bone regulation map to mid-distal mouse Chromosome 4 that shares linkage homology to human Chromosome 1p36

The mid-distal region of mouse chromosome 4 (Chr 4) is homologous with human Chr 1p36. Previously, we reported that mouse Chr 4 carries a QTL with strong regulatory effect on vBMD. The intent of this report is to utilize nested congenic strains to decompose the genetic complexity of this gene rich r...

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Bibliographic Details
Main Authors: Beamer, Wesley G., Shultz, Kathryn L., Coombs, Harold F., Horton, Lindsay G., Donahue, Leah Rae, Rosen, Clifford J.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460065/
https://ncbi.nlm.nih.gov/pubmed/22031020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.515
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