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Downregulation of Genes Involved in Metabolism and Oxidative Stress in the Peripheral Leukocytes of Huntington's Disease Patients

BACKGROUND: Huntington's disease (HD) is caused by expanded CAG repeats encoding a polyglutamine tract in the huntingtin (HTT) protein. A number of differentially-expressed protein molecules have been identified in striatum of HD animal models. Here we examined if the expression changes could b...

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Autors principals: Chang, Kuo-Hsuan, Chen, Yi-Chun, Wu, Yih-Ru, Lee, Wan-Fen, Chen, Chiung-Mei
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3459918/
https://ncbi.nlm.nih.gov/pubmed/23029535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046492
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