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Management of bone metastases in refractory prostate cancer – role of denosumab

This article reviews the problem of bone disease in prostate cancer and the evolving role of the novel agent denosumab, a fully human monoclonal antibody that inhibits the receptor activator of nuclear factor-κB ligand, in suppressing bone resorption and offering bone protection in this disease. Pro...

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Detalhes bibliográficos
Main Authors: Paller, Channing J, Carducci, Michael A, Philips, George K
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3459574/
https://ncbi.nlm.nih.gov/pubmed/23049248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CIA.S27930
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