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Molecular basis of reovirus neurovirulence: role of the M2 gene in avirulence.

A number of field isolates of reovirus 3 were examined to determine their relative neurovirulence after intracerebral inoculation. One isolate was found that had decreased neurovirulence. This "avirulent" strain showed the typical type 3 neural tropism but grew significantly less well in b...

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Autori principali: Hrdy, D B, Rubin, D H, Fields, B N
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1982
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC345950/
https://ncbi.nlm.nih.gov/pubmed/6951176
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