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Human “Orchestrator” CD11b(+) B1 Cells Spontaneously Secrete Interleukin-10 and Regulate T-Cell Activity

Immune regulation produced by B cells has been attributed to production and secretion of interleukin (IL)-10, which is a characteristic of mouse B1 cells. In view of the widespread clinical use of B-cell depletion therapies in autoimmune and malignant diseases, it is important to monitor the functio...

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Bibliographic Details
Main Authors: Griffin, Daniel O, Rothstein, Thomas L
Format: Artigo
Language:Inglês
Published: ScholarOne 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3459484/
https://ncbi.nlm.nih.gov/pubmed/22634719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2012.00203
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