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Signaling to Cardiac Hypertrophy: Insights from Human and Mouse RASopathies

Cardiac hypertrophy is the heart’s response to a variety of extrinsic and intrinsic stimuli, some of which might finally lead up to a maladaptive state. An integral part of the pathogenesis of the hypertrophic cardiomyopathy disease (HCM) is the activation of the rat sarcoma (RAS)/RAF/MEK (mitogen-a...

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Hlavní autoři: Sala, Valentina, Gallo, Simona, Leo, Christian, Gatti, Stefano, Gelb, Bruce D, Crepaldi, Tiziana
Médium: Artigo
Jazyk:Inglês
Vydáno: ScholarOne 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3459479/
https://ncbi.nlm.nih.gov/pubmed/22576369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2011.00512
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