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Gonadotropin stimulation contributes to an increased incidence of epimutations in ICSI-derived mice

We previously demonstrated that intracytoplasmic sperm injection (ICSI), a type of assisted reproductive technology (ART), can induce epimutations and/or epimutant phenotypes in somatic tissues of adult mice produced by this method. In the present study, we compared the occurrence of epimutations in...

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Библиографические подробности
Главные авторы: de Waal, Eric, Yamazaki, Yukiko, Ingale, Puraskar, Bartolomei, Marisa S., Yanagimachi, Ryuzo, McCarrey, John R.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3459467/
https://ncbi.nlm.nih.gov/pubmed/22802074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds287
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