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Penetrance rate estimation in autosomal dominant conditions

Accurate estimates of the penetrance rate of autosomal dominant conditions are important, among other issues, for optimizing recurrence risks in genetic counseling. The present work on penetrance rate estimation from pedigree data considers the following situations: 1) estimation of the penetrance r...

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Bibliografiske detaljer
Main Authors: Otto, Paulo A., Horimoto, Andréa R.V.R.
Format: Artigo
Sprog:Inglês
Udgivet: Sociedade Brasileira de Genética 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3459406/
https://ncbi.nlm.nih.gov/pubmed/23055795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/S1415-47572012005000051
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