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Molecular basis for the diagnosis and treatment of acute promyelocytic leukemia

Acute promyelocytic leukemia is characterized by gene rearrangements that always involve the retinoic acid receptor alpha on chromosome 15. In the majority of patients t(15;17) is detected, which generates the promyelocytic leukemia gene/retinoic acid receptor alpha rearrangement. This rearrangement...

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Detalhes bibliográficos
Main Authors: Bassi, Sarah Cristina, Rego, Eduardo Magalhães
Formato: Artigo
Idioma:Inglês
Publicado em: Associação Brasileira de Hematologia e Hemoterapia 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3459394/
https://ncbi.nlm.nih.gov/pubmed/23049403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5581/1516-8484.20120033
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