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Somatic mutation in a cultured mouse myeloma cell affects antigen binding.

The S107 mouse myeloma cell line synthesizes an IgA antibody that binds the hapten phosphocholine and is similar if not identical in its heavy and light chain variable region sequence to the predominant antibody produced by BALB/c mice in response to immunization with phosphocholine. This cell line...

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Bibliografiske detaljer
Main Authors: Cook, W D, Rudikoff, S, Giusti, A M, Scharff, M D
Format: Artigo
Sprog:Inglês
Udgivet: 1982
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC345937/
https://ncbi.nlm.nih.gov/pubmed/6803237
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