Inhibition of SIRT2 Potentiates the Anti-motility Activity of Taxanes: Implications for Antineoplastic Combination Therapies

Taxanes are potent inhibitors of cell motility, a property implicated in their antiangiogenic and antimetastatic activity and unrelated to their antiproliferative effect. The molecular mechanism of this anti-motility activity is poorly understood. In this study, we found that paclitaxel induced tubu...

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Hlavní autoři: Bonezzi, Katiuscia, Belotti, Dorina, North, Brian J, Ghilardi, Carmen, Borsotti, Patrizia, Resovi, Andrea, Ubezio, Paolo, Riva, Antonella, Giavazzi, Raffaella, Verdin, Eric, Taraboletti, Giulia
Médium: Artigo
Jazyk:Inglês
Vydáno: Neoplasia Press Inc. 2012
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3459280/
https://ncbi.nlm.nih.gov/pubmed/23019416
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