Appearance of crystalloid endoplasmic reticulum in compactin-resistant Chinese hamster cells with a 500-fold increase in 3-hydroxy-3-methylglutaryl-coenzyme A reductase.

We have developed a line of Chinese hamster ovary cells with a 500-fold increase in 3-hydroxy-3-methylglutaryl-coenzyme A reductase, the membrane-bound enzyme that controls cholesterol synthesis. This line, designated (UT-1, was obtained by stepwise adaptation of cells to growth in increasing concen...

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Bibliografski detalji

Izdano u:	Proc Natl Acad Sci U S A
Glavni autori:	Chin, D J, Luskey, K L, Anderson, R G, Faust, J R, Goldstein, J L, Brown, M S
Format:	Artigo
Jezik:	Inglês
Izdano:	National Academy of Sciences 1982
Teme:	Research Article
Online pristup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345926/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6951166/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.4.1185
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