Immune Dysregulation, Polyendocrinopathy, Enteropathy, X-Linked Syndrome: A Paradigm of Immunodeficiency with Autoimmunity

Immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome is a rare monogenic primary immunodeficiency (PID) due to mutations of FOXP3, a key transcription factor for naturally occurring (n) regulatory T (Treg) cells. The dysfunction of Treg cells is the main pathogenic event l...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Barzaghi, Federica, Passerini, Laura, Bacchetta, Rosa
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Research Foundation 2012
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3459184/
https://ncbi.nlm.nih.gov/pubmed/23060872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2012.00211
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi