FIBRONECTIN-α4β1 INTERACTIONS IN HEPATIC COLD ISCHEMIA REPERFUSION INJURY: REGULATION OF MMP-9 AND MT1-MMP VIA THE p38 MAPK PATHWAY

Liver ischemia-reperfusion injury (IRI) remains a challenging problem in clinical settings. The expression of fibronectin (FN) by endothelial cells is a prominent feature of the hepatic response to injury. Here we investigate the effects of the connecting segment-1 (CS-1) peptide therapy, which bloc...

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Autores principales: Duarte, Sergio, Shen, Xiu-Da, Fondevila, Constantino, Busuttil, Ronald W., Coito, Ana J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3459169/
https://ncbi.nlm.nih.gov/pubmed/22812390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2012.04161.x
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